What is the target range for blood glucose levels in critically ill patients?

The target range for blood glucose levels in critically ill patients is typically set at 140-180 mg/dL. This range is based on clinical guidelines and evidence indicating that maintaining blood glucose within this threshold can help to reduce complications associated with hyperglycemia, such as infection rates, mortality, and prolonged hospital stays.

In critically ill patients, particularly those with stress-induced hyperglycemia, a more lenient target is often implemented rather than stricter targets seen in non-critical settings. Keeping glucose levels between 140 and 180 mg/dL balances the need to avoid the detrimental effects of both hyperglycemia and hypoglycemia while promoting better overall outcomes. Research has shown that aiming for this range is associated with fewer negative effects compared to lower targets, especially in patients with certain medical conditions or those undergoing surgery.

This approach is reflected in guidelines from organizations such as the American Diabetes Association and the American Association of Clinical Endocrinologists, which recommend this target specifically for critically ill patients to optimize their overall management.